Enhancing Surgical Safety in Liver Procedures with Advanced Haemostats – Hepatitis Day 2025

Enhancing Surgical Safety in Liver Procedures with Advanced Haemostats – Hepatitis Day 2025

 World Hepatitis Day 2025, observed on 28 July, raises awareness about viral hepatitis, a critical global health challenge that led to 1.3 million deaths from chronic hepatitis B and C worldwide. ¹

These infections often progress to advanced liver disease and liver cancer, requiring complex surgical interventions such as hepatectomy, liver resections, or transplants. One of the major challenges during these procedures is controlling bleeding, as the liver’s dense vascular structure makes haemostasis particularly difficult.

Rapid and effective bleeding control is essential to minimize blood loss and ensure better surgical outcomes. While conventional techniques like manual pressure, suturing, ligation, clipping, and cauterization are commonly used, they may not always be sufficient or feasible in every case. In such cases, advanced hemostatic agents such as SURGISPON®, FLOGEL®, and SurgiORC®play a crucial role in managing bleeding efficiently and safely during these critical procedures.

  1. SURGISPON®: Quick-acting Absorbable Hemostatic Gelatin Sponge

It is a quick and effectively controls bleeding.It is non-toxic, non-allergenic, non-immunogenic, non-pyrogenic, and gamma-sterilized, requiring no resterilization or special storage. Its uniform porosity ensures effective hemostasis.

Why use SURGISPON®

Fig 1: SURGISPON® Absorbable Hemostatic Sponges

Clinical Evidence:

Evaluated the safety and efficacy of tract embolization with gelatin sponge strips after percutaneous transhepatic poral vein access.Between September 2017 and February 2024, 100 patients (61 men, 39 women) underwent 105 percutaneous transhepatic portal vein interventions, including 71 pre-hepatectomy embolizations, 27 post-transplant venoplasties or stent placements, and 7 other procedures.Gelatin sponge strips were used after 6–8 Fr sheath removal, with no bleeding observed. Minor, non-significant portal vein thrombosis occurred in 4 cases, with no clear association to the sponge or sheath. The technique proved safe and effective for bleeding prevention.2

  1. FLOGEL®: Flowable Gelatin Haemostatic Matrix for Hard-to-reach Bleeding Sites

It isan off-white, flowable gelatin haemostatic matrix made from absorbable sponge and prefilled in a syringe It is designed for bleeding control in tight, irregular, and hard-to-reach surgical sites.Maintains consistent viscosity after mixing with saline or thrombin; available in 5 ml, 6 ml, 8 ml, and 10 ml kits.

Why use FLOGEL®:

Fig 2: FLOGEL® Flowable Gelatin Haemostatic Matrix Kit

Clinical Evidence:

This prospective study assessed 83 hepatectomy patients where Floseal® was applied to 87 bleeding sites, graded using the Validated Intraoperative Bleeding (VIBe) Scale. Complete hemostasis was achieved in all cases. A 2-minute initial application succeeded in 100% of VIBe grade 1, 76% of grade 2, 20% of grade 3, and none of grade 4 cases. No bleeding-related complications were observed, supporting Floseal® as a safe and effective haemostatic agent for liver resections.3

Fig 3: Gelatin-thrombin matrix sealants (Floseal®) for haemostasis during liver resection3

  1. Surgi-ORC®: Plant-Based Hemostatic Solution (Oxidized Regenerated Cellulose)

It is a sterile, plant-based absorbable haemostat made of oxidized regenerated cellulose (polyoxyan hydro glucuronic acid). It offers high stability and superior fluid absorption and can be cut into desired sizes for surgical procedures.

Variants for procedure:

Surgi-ORC ORIGINAL-A flexible, drapable haemostatic dressing for effective surgical use.

Surgi-ORC KNIT-Suture-friendly and suitable for bleeding control in laparoscopic and transplant surgeries.

Why use Surgi-ORC®:

Fig 4: Surgi-ORC® Absorbable Haemostat (Oxidized Regenerated Cellulose)

Clinical Evidence:

In a randomized trial of 40 hepatectomy patients, prophylactic application of oxidized regeneratedcellulose (ORC) significantly reduced postoperative drainagein ORC group compared with the control group(406.9 ± 308.1 mlvs. 627.0 ± 301.6 ml; p=0.028), enhanced hemostasis, and minimized liver resection-related complications, highlighting its effectiveness in improving surgical outcomes.4

Promoting Liver Health for a Better Future

On World Hepatitis Day 2025, let’s emphasize the importance of liver health by advocating for:

  • Awareness & early detection of hepatitis to prevent liver complications.
  • Preventive care in chronic liver disease5
  • Encouraging healthy lifestyle habits to protect and support liver function.
  • Advancing hemostatic solutions for safer liver surgeries and improved patient outcomes.

At Aegis Lifesciences, we are committed to transforming liver care with surgical solutions that support healthcare professionals in managing complex hepatic challenges. This World Hepatitis Day, let’s work together to raise awareness, drive advancements in treatment, and empower patients with better care for a healthier future.

Comments

Post a Comment

Popular posts from this blog

Revolutionizing Surgical Hemostasis: Introducing Surgi-ORC® Powder (Absorbable Hemostatic Powder)

Image
  In modern surgery, efficiently managing perioperative bleeding is crucial. Uncontrolled surgical bleeding poses significant risks to patient health and leads to substantial clinical and healthcare resource burdens. This challenge is particularly pronounced with an aging population and the rising prevalence of comorbidities and anticoagulant use. To address these issues, topical hemostatic agents have emerged as vital tools, promoting hemostasis where conventional methods fall short. These agents vary widely in properties, mode of action, ease of use, safety, and cost. Their selection often depends on the specific surgical scenario, bleeding situation, and patient’s health status. Exploring Topical Hemostatic Agents The current array of topical hemostatic agents comprises several types, each designed to meet different needs in the surgical setting: Mechanical Agents:  These are regarded as the simplest, safest, and most cost-effective. They offer a structural framework for he...
Read more

The Role of Haemostatic Gel Matrix in Reducing Neurosurgical Complications

Image
  Neurosurgical procedures demand exceptional precision and control, especially when performed in tight anatomical spaces using microscopic or endoscopic techniques. In such confined environments, even minor bleeding can significantly obscure the surgical field, increasing operative complexity and the risk of damaging critical neural structures [1]. Thus, achieving rapid and effective haemostasis is not merely desirable — it is vital to patient safety and surgical success. Why Haemostasis Matters in Neurosurgery Unlike many other surgical specialties, neurosurgery poses distinct challenges due to the proximity of vital neural structures and the potentially devastating consequences of even minor postoperative bleeding. Generalized oozing from the dura mater, spinal nerves, or bony surfaces may be deceptively persistent and difficult to control. Residual blood, even in small amounts, can compress delicate tissues, resulting in complications such as hematomas, infections, or neurologi...
Read more

The Future of Dialysis Care – Harnessing hemostatic dialysis bandages for effective vascular management

Image
  Dialysis Overview Kidneys help filter waste from the blood, keep body fluids balanced, and produce essential hormones. When kidneys fail due to disease or injury, dialysis becomes a lifesaving treatment. In people with end-stage kidney disease, or kidney failure, dialysis takes over the kidney’s role by removing extra waste and fluid from the blood. When is Dialysis Needed? Dialysis is recommended when a person’s kidney function drops to 10-15%. This typically occurs in the final stage of chronic kidney disease [1]. Dialysis can also be required in cases of acute kidney failure, where the kidneys suddenly lose their ability to function. What is Haemodialysis? Haemodialysis is the most common form of dialysis. It performs the job of the kidneys when they can no longer function properly. This process involves drawing blood from the body, filtering it through a machine called a dialyzer (an artificial kidney), and then returning the cleaned blood back to the body. Haemodialysis help...
Read more